ABSTRACT Breast cancer is one of the biggest global dilemmas and its current therapy is to target the hormone receptors by the use of partial agonists/antagonists. Potent drugs for breast cancer treatment are Tamoxifen, Trastuzumab, Paclitaxel, etc. which show adverse effects and resistance in patients. The aim of the study has been on certain phytochemicalsRead More
Involvement of estrogen receptor α in pro-pruritic and pro-inflammatory responses in a mouse model of allergic dermatitis
ABSTRACT It has been reported that endogenous or exogenous estrogens can affect the immune system, resulting in immune disorders; however, their direct involvement in such conditions remains to be demonstrated. The purpose of this study was to investigate whether estrogen receptors (ER) are directly implicated in pro-pruritic and pro-inflammatory reactions in cutaneous allergy. Initially, enhancement of the pro-inflammatoryRead More
Estrogen Receptor Alpha (ERα; NR3A1)
Estrogen Receptor Alpha (ERα; NR3A1) Product Family Product Number Product Description Technical Manual IB0040 ERα (NR3A1) IB00401-32 Human ERα Reporter Assay System, 3 x 32 assays in 96-well format Technical Manual IB00401 Human ERα Reporter Assay System, 1 x 96-well format assays Technical Manual IB00402 Human ERα Reporter Assay System, 1 x 384-well format assaysRead More