View Full Size Research conducted by: Samaar Maalouf (1), Bruce Sherf(1), & Jack Vanden Huevel (1,2) (1) INDIGO Biosciences, Inc., 1981 Pine Hall Road, State College, PA, USA (2) Center for Molecular Toxicology and Carcinogenesis, 325 Life Sciences Building, Penn State University, University Park, PA 16802, USA Date of publication: 2017
Effects of cranberry extracts on gene expression in THP-1 cells
ABSTRACT Cranberry contains high levels of nutrients and bioactive molecules that have health-promoting properties. The purpose of the present studies was to determine if cranberry extracts (CEs) contain phytochemicals that exert anti-inflammatory effects. The human monocytic cell line THP-1 was treated with two CEs (CE and 90MX) and subsequently challenged with Lipopolysaccharides (LPS). Tumor necrosisRead More
Inhibition of Mitochondrial Gene Expression by Nucleoside Analogues and Delayed Mitochondrial Dysfunction
View Full Size Research conducted by: Midhun Korrapati(1), Koji Toyokawa (1), Bruce Sherf (1), & Jack Vanden Huevel (1,2) (1) INDIGO Biosciences, Inc., 1981 Pine Hall Rd, State College, PA, USA (2) Center for Molecular Toxicology and Carcinogenesis, 325 Life Sciences Building, Penn State University, University Park, PA 16802, USA Date of publication: March 2016
INDIGO Now Offers Profiling of Genes Regulated by Nuclear Receptors
“Critical Step in Understanding the downstream genomic impact of interactions with nuclear receptors” State College, Pennsylvania, July 23, 2015 INDIGO Biosciences Inc., a recognized industry-leading provider of nuclear receptor products and services, announced today that it has expanded its service portfolio by offering analyses of nuclear receptor regulated genes. Gene expression is a widely used approachRead More