ABSTRACT While alternative methods for toxicity testing using re-constructed human skin and cornea have been written into guidelines and adopted by regulatory authorities, three-dimensional (3D) liver models are currently applied in the industrial settings for hepatotoxicity screening and prediction. These 3D liver models can recapitulate the architecture, functionality and toxicity response of the native liver,Read More
Development of a High-Throughput CYP Induction Assay by mRNA Measurement in Human Primary Hepatocytes
View Full Size Research conducted by: Ryan Wulf (1) & Yong Zhao (1) (1) Eurofins Pharma Discovery Services, 15 Research Park Drive, St. Charles, MO 63304 Date of Publication: 2017 Presented at: ISSX 2017 in Providence, RI