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  • HOME
  • ABOUT
    • About
    • Why INDIGO
    • Key Personnel
      • Board of Directors & Advisors
      • Management
  • PRODUCTS
    • Assays
    • Ortholog Assays
    • Growth Factor Receptors
    • In Vitro Toxicology Platform
    • MDR1 / Human P-Glycoprotein
    • Gene Expression
    • NASH Nuclear Receptors For Research
    • Disease States
    • Live Cell Multiplex
    • Custom Assay Development
  • TECHNICAL
    • Nuclear Receptor Profiling & Panels
    • Assay Kit Platform & Formats
    • FAQ
    • Discovery Toxicology
    • upcyte® Hepatocytes
    • Technical Manuals & Product Listing
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Three-dimensional liver models: state of the art and their application for hepatotoxicity evaluation

ABSTRACT While alternative methods for toxicity testing using re-constructed human skin and cornea have been written into guidelines and adopted by regulatory authorities, three-dimensional (3D) liver models are currently applied in the industrial settings for hepatotoxicity screening and prediction. These 3D liver models can recapitulate the architecture, functionality and toxicity response of the native liver,Read More

Filed Under: New Publications Tagged With: 3D liver model, Hepatocytes, hepatotoxicity, liver injury, spheroid

INDIGO Biosciences Announces Release of Predictive Liver Toxicity Assay Kit

By combining the advantages of upcyte hepatocytes with INDIGO’s industry-leading platform and science, the new hepatotoxicty assay kit helps researchers get the information they need to confidently advance their discovery processes.

Filed Under: press Tagged With: hepatotoxicity, In Vitro Toxicology, upcyte hepatocytes

Detection of cytokeratin 18 in proliferating, primary-like upcyte® hepatocytes to predict drug-induced hepatotoxicity

Detection of cytokeratin 18 in proliferating, primary-like upcyte® hepatocytes to predict drug-induced hepatotoxicity

View Full Size Research conducted by: Wiebe Schaefer (1), Astrid Noerenberg (1), Adrian Kling (2), Giannella Coghlan (2), Nils Runge (1), & Timo Johannssen (1) (1) upcyte technologies GmbH, Osterfeldstr. 12-14, 22529 Hamburg, Germany (2) VLVbio AB, Hästholmsvägen 32, 13130 Nacka, Sweden Date of Publication: 2017

Filed Under: New Publications, Posters Tagged With: hepatotoxicity, upcyte, upcyte hepatocytes

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