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Bergapten inhibits liver carcinogenesis by modulating LXR/PI3K/Akt and IDOL/LDLR pathways

ABSTRACT Oxysterol receptors LXRs (α and β) are recently reported to be one of the novel and potential therapeutic targets in reducing cell proliferation and tumor growth in different system model. Activation of LXRs is correlated with modification of PI3K/Akt pathway. LXRs are also found to play a critical role in maintaining lipid homeostatais byRead More

Filed Under: New Publications Tagged With: Bergapten, Hepatocellular carcinoma, IDOL, LDLR, lipid metabolism, LXR, LXRα, LXRβ, PI3K

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