Nuclear Receptor & In Vitro Toxicology Solutions™

Get all the latest news from INDIGO

  • This field is for validation purposes and should be left unchanged.

  • ABOUT
    • About INDIGO
    • Why INDIGO
    • Key Personnel
      • Board of Directors & Advisors
      • Management
    • Employment
    • INDIGO Press Releases
    • INDIGO in the News
  • ASSAYS
    • By Receptor
    • By Disease State
      • Overview
      • Anemia & Kidney Disease
      • Autoimmune Disease & Inflammation
      • Cancer
      • Cardiovascular Disease
      • Diabetes
      • Endocrinology
      • NAFLD/NASH
      • Obesity
    • Toxicology Solutions
      • In Vitro Toxicology Platform
      • Gene Expression
      • MDR1 / Human P-Glycoprotein
      • Discovery Toxicology
      • Environmental Monitoring
    • INDIGlo Luciferase Detection Reagent
    • Live Cell Multiplex
    • Ortholog Assays
    • Custom Assay Development
  • TECHNOLOGY
    • Nuclear Receptor Overview
    • Assay Kit Platform & Formats
    • Nuclear Receptor Profiling & Panels
    • Environmental Testing Solutions
    • Growth Factor Receptors
    • upcyte® Hepatocytes
    • FAQ
  • RESOURCES
    • Technical Manuals
    • Safety Data Sheets
    • Scientific Whitepapers from INDIGO
    • Scientific Posters
    • New Research Publications
    • Nuclear Receptor Resource
  • CONTACT US
    • Contact INDIGO
    • Request a Quote
    • Request Information
    • Distributors
    • Terms & Conditions
      • Product Policies
      • Limited Use Disclosures
  • BLOG

Nuclear Receptor & In Vitro Toxicology Solutions™

Search site...

± α β γ δ Δ ε ζ κ ω ö ® ™ µ

  • ABOUT
    • About INDIGO
    • Why INDIGO
    • Key Personnel
      • Board of Directors & Advisors
      • Management
    • Employment
    • INDIGO Press Releases
    • INDIGO in the News
  • ASSAYS
    • By Receptor
    • By Disease State
      • Overview
      • Anemia & Kidney Disease
      • Autoimmune Disease & Inflammation
      • Cancer
      • Cardiovascular Disease
      • Diabetes
      • Endocrinology
      • NAFLD/NASH
      • Obesity
    • Toxicology Solutions
      • In Vitro Toxicology Platform
      • Gene Expression
      • MDR1 / Human P-Glycoprotein
      • Discovery Toxicology
      • Environmental Monitoring
    • INDIGlo Luciferase Detection Reagent
    • Live Cell Multiplex
    • Ortholog Assays
    • Custom Assay Development
  • TECHNOLOGY
    • Nuclear Receptor Overview
    • Assay Kit Platform & Formats
    • Nuclear Receptor Profiling & Panels
    • Environmental Testing Solutions
    • Growth Factor Receptors
    • upcyte® Hepatocytes
    • FAQ
  • RESOURCES
    • Technical Manuals
    • Safety Data Sheets
    • Scientific Whitepapers from INDIGO
    • Scientific Posters
    • New Research Publications
    • Nuclear Receptor Resource
  • CONTACT US
    • Contact INDIGO
    • Request a Quote
    • Request Information
    • Distributors
    • Terms & Conditions
      • Product Policies
      • Limited Use Disclosures
  • BLOG

Nuclear Hormone Receptors

Nuclear Hormone Receptor General Overview Nuclear Hormone Receptor Introduction Unlike receptors found on the cell surface, members of the nuclear hormone receptor (NR) superfamily are restricted to metazoan organisms such as nematodes, insects, and vertebrates. These proteins are intracellular transcription factors that directly regulate gene expression in response to lipophilic molecules. They affect a wideRead More

Nuclear Receptor Assays

Nuclear Receptor Assays INDIGO’s Nuclear Receptor Assays are reporter assays for  intracellular transcription factors that directly regulate gene expression in response to lipophilic molecules commonly referred to as nuclear receptors (NRs). Nuclear receptors affect a wide variety of functions, including fatty acid metabolism, reproductive development, and detoxification of foreign substances. Many NRs act as ligand-inducibleRead More

Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos

ABSTRACT Triphenyl phosphate (TPHP) is an unsubstituted aryl phosphate ester used as a flame retardant and plasticizer within the United States. Using zebrafish as a model, the objectives of this study were to rely on (1) mRNA-sequencing to uncover pathways disrupted following embryonic TPHP exposure and (2) high-content screening to identify nuclear receptor ligands thatRead More

Filed Under: New Publications Tagged With: cardio toxciity, nuclear receptor, nuclear receptor signaling, ortholog, RXR, triphenyl phosphate, zebrafish

INDIGO Offers NF-κB Assay Systems

New Assay Critical to the Study of the Human Immune Responses and Cancers State College, PA (October 16, 2014) – INDIGO Biosciences, a leading provider of nuclear receptor products and services announced today that it has released a new nuclear factor kappa-light-chain enhancer of activated B cells (NF-κB) assay system. Three different assay kit formatsRead More

Filed Under: press Tagged With: assay, kappa, NF-kB, nuclear receptor

INDIGO Offers Human Estrogen-related Receptor Gamma Assay System

New Assay to Test Target Compounds for Anti-Obesity Therapeutics State College, PA (September 18, 2014) – INDIGO Biosciences, a leading provider of nuclear receptor products and services announced today that it has released a new Human Estrogen-related Orphan Receptor Gamma (NR3B3; ERRγ) Assay System. Three different assay kits are available. ERRg is naturally expressed inRead More

Filed Under: press Tagged With: assay, Errg, ERRγ, gamma, nuclear receptor, therapeutic target

New Human Aryl Hydrocarbon Receptor Reporter Assay System Kit Offers Convenience, Assay Sensitivity and Reliable Results

State College, PA (August 14, 2014) – INDIGO Biosciences, a research products and services company focused on nuclear receptor screenings, announced today that it has released new cell-based Aryl Hydrocarbon Receptor (AhR) reporter assay kits.  The Aryl Hydrocarbon Receptor (AhR) Assay employs the luciferase reporter gene technology, and is used for screening test samples toRead More

Filed Under: press Tagged With: AhR, assay, hydrocarbon receptor, nuclear receptor

INDIGO Biosciences - The right partner for all your discovery and toxicology needs.
Search site...
Click to Insert Symbols in Search

α β γ δ Δ ε ζ κ ® ™ µ

Want More Information?

Simply fill out this form and we'll be in touch!

Resource Quick Links

  • Technical Manuals & Product Listing
  • Safety Data Sheets
  • Sample Study Report
  • Study Work Order Form

3006 Research Drive, Suite A1, State College, PA, USA 16801

+1 (814) 234-1919

  • Home
  • Products
  • Request a Quote
  • FAQ

© 2022 INDIGO Biosciences, Inc. All Rights Reserved