Blogs Hepatocyte Nuclear Factor 4 Alpha in Disease and Drug Discovery Hepatocyte Nuclear Factor 4 Alpha in Disease and Drug Discovery The Hepatocyte Nuclear Factor 4 Alpha (HNF4α) What is the Hepatocyte Nuclear Factor 4 Alpha (HNF4α)? The Hepatocyte Nuclear Factor 4 Alpha (HNF4a) belongs to the nuclear receptor superfamily, serving as a critical transcription…

Blogs Understanding Assay Performance Metrics Understanding Assay Performance Metrics When embarking on the search for a reliable cell-based assay, it’s common practice to start by typing “Receptor X cell-based assay” into the search bar of your preferred internet browser. From there, you navigate through the multitude of search results, sifting through the information provided. This…

Blogs Oxytocin Receptor in Disease and Drug Discovery Oxytocin Receptor in Disease and Drug Discovery The Oxytocin Receptor (OXTR) What is the Oxytocin Receptor (OXTR)? The Oxytocin Receptor (OXTR) is a vital component of the human body’s neuroendocrine system, primarily associated with social behavior, reproductive functions, and emotional regulation. The Oxytocin Receptor belongs to the…

Blogs Alpha-1 Adrenergic Receptors in Disease and Drug Discovery Alpha-1 Adrenergic Receptors in Disease and Drug Discovery Adrenergic receptors, a class of G protein-coupled receptors (GPCRs), play a pivotal role in mediating the physiological effects of the sympathetic nervous system which is responsible for “fight-or-flight” response. These receptors are integral components of the human body’s…

Blogs Adrenergic Receptors In Disease and Drug Discovery Adrenergic Receptors In Disease and Drug Discovery Adrenergic receptors, a class of G protein-coupled receptors (GPCRs), play a pivotal role in mediating the physiological effects of the sympathetic nervous system which is responsible for the “fight-or-flight” response. These receptors are integral components of the human body’s response…

Blogs Therapeutic Drug Repurposing: Finding New Applications for Existing Drugs through Nuclear Receptor Profiling Therapeutic Drug Repurposing: Finding New Applications for Existing Drugs through Nuclear Receptor Profiling What is Drug Repurposing? As drug discovery continues to look towards smaller and smaller patient pools and hyper-specific disease states, the demand for new drugs grows rampant. Combined…