Environmental Testing Solutions from INDIGO
INDIGO’s effects-based bioassay solutions compliment traditional analytical chemistry approaches for the examination of water quality and can help protect human and environmental health.
Are Traditional Water Quality Methods Enough?
Traditional techniques rely on analyses and data for individual contaminants. Real world exposure generally occurs as mixtures of different chemical compounds. According to the EPA this presents risks posed to humans and the environment from:
- chemicals without toxicity information
- the presence and concentrations of other compounds
- chemicals that work together to increase the toxic potential
To understand the risk posed by complex samples cell-based assay are needed to characterize cumulative effects on humans and other organisms.
Cell-Based Assays: The Next Wave in Evaluating Water Quality
Cell-based reporter assays such as those provided by INDIGO Biosciences screen for total bioactivity for a specific pathway of importance. They can detect the toxicity of unknown chemicals and can account for the cumulative effects simplifying the issues posed by complex mixtures in analytical methods. INDIGO has an extensive list of cellular bioassays that are predictive of cellular toxicity pathways including endocrine disruption, altered xenobiotic metabolism and adaptive stress responses.
INDIGO's assays can detect the cumulative effect of bioactive compounds in extracted environmental matrices and provide important biological context. They are:
- All-Inclusive
- Sensitive
- Cost Effective
- Reproducible
- and Easy to Perform
Learn more about INDIGO Biosciences’ Assay Kit Platforms & Formats
INDIGO has an extensive list of bioassay kits for receptors important in Environmental Monitoring for contaminant detection and quantification in samples which include:
Endocrine Disruption
Xenobiotic Metabolism
Lipid and Energy Metabolism
Basal metabolism
Our receptor specific assays are cell-based reporter assay systems. They feature engineered receptor-specific reporter cells prepared using our unique CryoMite™ process. Once thawed, reporter cells are ready for immediate use. Test compounds can be screened for agonist or antagonist activities against receptors.
INDIGO Biosciences works closely with clients to provide the appropriate reporter specific assays for their water testing needs. Our technology generates clear single receptor or full-panel screening results. Employing a luminescence-based method and our proprietary CryoMite™ preservation process, INDIGO kits provide reproducible results lot-to-lot.
Learn more about INDIGO Biosciences’ Assay Kit Platforms & Formats