Toxicology Assay Kits
Rapidly assess therapeutic candidates’ potential for drug-drug interactions and accurately predict xenobiotic-induced liver toxicity. INDIGO’s toxicology assay kits provide rapid, reliable results for:
Showing all 5 results
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Human CAR-3 Reporter Assay Kit
Species
Human
Target Type
Nuclear Hormone Receptor
Associated Disease
NASH/NAFLD, Wound Healing
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Human Nrf2 Reporter Assay Kit
Species
Human
Target Type
Transcription Factor
Associated Disease
Cancer, Cardiovascular, NASH/NAFLD, Neurodegenerative, Obesity, Reproduction
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Human PXR Reporter Assay Kit
Species
Human
Target Type
Nuclear Hormone Receptor
Associated Disease
Cancer, Cardiovascular, Kidney Disease, NASH/NAFLD, Wound Healing
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in vitro Screening for Drug-Induced Hepatotoxicity Assay Kit
Species
Human
The principal application of this assay is to rapidly screen test compounds to identify those that induce acute liver cell toxicity.
This kit includes two aliquots of cryopreserved Luminescent Reporter Hepatocytes (upcyte®), donor 10-13, isolated from an adult Caucasian female, that have been further modified to constitutively express the luciferase enzyme. In addition to two aliquots of the reporter hepatocytes, the kit provides two cell culture-ready assay plates, optimized Cell Culture Media (CCM) for use in all steps of the assay procedure (cell thawing, seeding, and preparation of the treatment media), luciferase detection reagent, and a reference compound that provides a positive control for hepatotoxicity.
The reagents and materials provided in this assay kit are formatted to allow the user to choose between two alternative assay setups. In one scenario 48 culture wells may be setup at two different times. In the other assay scenario 96 culture wells may be setup at one time.
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Mouse PXR Reporter Assay Kit
Species
Mouse
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cancer, Cardiovascular, Kidney Disease, NASH/NAFLD, Wound Healing