The Vitamin D3 Receptor (VDR) is INDIGO Biosciences newest product in the company’s variety of robust cell-based nuclear receptors; VDR is now available for our in-house screening services or as a complete cell-based INDIGO Assay Kits for your drug discovery and development research.
Bring the expertise of INDIGO Biosciences into your lab using INDIGO’s robust Assay kits, available for all of our nuclear receptors. Our easy-to-use Assay reporter kits will provide you with quick and accurate results using our simple four step process: Thaw, Feed, Dose, Read. INDIGO’s Assay kits include a cell culture ready assay plate, a positive control ligand, and reporter cells. INDIGO’s kits will provide you with results in 24 hours, showing excellent Z’ scores and high signal-to-noise ratio. Our kits are available in 1x 96, 3x 32, or 1x 384- well formats. INDIGO offers over 30 different human and rat and mouse ortholog assay kits.
In addition to our Assay kits, INDIGO’s nuclear receptor experts can provide you with our in-house screening services. Send us your compounds and we are happy to run the Assays here in our lab, providing you with the quick and accurate results you need.
VDR is a 1,25 di-hydroxyvitamin D3, part of group 1I1 in the ligand-induced transcription factors family, which include PXR and CAR-1, 2, 3. VDR dysfunction may be associated with immune, metabolic, and cardiovascular diseases, as well as cancer and bone disorders, commonly known as osteoporosis.