Toxicology Assay Kits
Rapidly assess therapeutic candidates’ potential for drug-drug interactions and accurately predict xenobiotic-induced liver toxicity. INDIGO’s toxicology assay kits provide rapid, reliable results for:
Showing all 7 results
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Cyn Monkey PXR Reporter Assay Kit
Species
Cyn Monkey
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cancer, Cardiovascular, Kidney Disease, NASH/NAFLD, Wound Healing
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Dog PXR Reporter Assay Kit
Species
Dog
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cancer, Cardiovascular, Kidney Disease, NASH/NAFLD, Wound Healing
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Human CAR-3 Reporter Assay Kit
Species
Human
Target Type
Nuclear Hormone Receptor
Associated Disease
NASH/NAFLD, Wound Healing
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Human P-Glycoprotein / MDR1 Drug Interaction Assay
Species
Human
The primary application of INDIGO Biosciences MDR1 drug interaction assay kit is to rapidly assess drug candidates as either inhibitors, substrates, or non-substrates of P-glycoprotein. This is accomplished by co-treating the cells with varying concentrations of the test drug and a fixed concentration of daunorubicin, a well-characterized fluorescent substrate for P-glycoprotein mediated transport. HCT-Pgp cells are a proprietary cell line that have been extensively selected for high-level expression of native P-glycoprotein.
The kit contains two aliquots of HCT-Pgp cells and two black, sterile, collagen-coated 96-well assay plates. In addition to HCT-Pgp cells and assay plates, this kit includes Cell Recovery Medium (CRM-p) used to perform a rapid thaw of the -80°C HCT-Pgp cells, Compound Screening Medium supplemented with daunorubicin (CSM+DR) used to prepare drug treatment media, Wash Buffer, two aliquots of Lysis Reagent, and the potent reference inhibitor Tariquidar.
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Human PXR Reporter Assay Kit
Species
Human
Target Type
Nuclear Hormone Receptor
Associated Disease
Cancer, Cardiovascular, Kidney Disease, NASH/NAFLD, Wound Healing
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Mouse PXR Reporter Assay Kit
Species
Mouse
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cancer, Cardiovascular, Kidney Disease, NASH/NAFLD, Wound Healing
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Rat PXR Reporter Assay Kit
Species
Rat
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cancer, Cardiovascular, Kidney Disease, NASH/NAFLD, Wound Healing