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PDFPosters related to Nuclear Receptors, Nuclear Receptor research, in vitro toxicology, and gene expression.
Detection of cytokeratin 18 in proliferating, primary-like upcyte® hepatocytes to predict drug-induced hepatotoxicity
Print PDF View Full Size Research conducted by: Wiebe Schaefer (1), Astrid Noerenberg (1), Adrian Kling (2), Giannella Coghlan (2), Nils Runge (1), & Timo Johannssen (1) (1) upcyte technologies GmbH, Osterfeldstr. 12-14, 22529 Hamburg, Germany (2) VLVbio AB, Hästholmsvägen 32, 13130 Nacka, Sweden Date of Publication: 2017
Use of upcyte® hepatocytes as a steatosis model on a multi-organ chip
Print PDF View Full Size Research conducted by: S. Bauer (2), C. Magauer (2), I. Maschmeyer (2), C. Drewell (1), A. Lorenz (2), N. Runge (3), T. Johannssen (3), U. Marx (2), & A. Noerenberg (3) (1) Technische Universität Berlin, Medizinische Biotechnologie (2) TissUse, Berlin, Germany (3) upcyte technologies GmbH, Osterfeldstr. 12-14, D-22529 Hamburg, Germany Date ofRead More
Profiling Drug Activity of Human and Ortholog Xenobiotic-Sensing Receptors: PXR, CAR, AhR, and FXR
Print PDF View Full Size Research conducted by: Koji Toyokawa (1), Ewa Maddox (1), Jack Vanden Huevel (1,2), & Bruce Sherf (1) (1) INDIGO Biosciences, Inc., 1981 Pine Hall Rd, State College, PA, USA (2) Center for Molecular Toxicology and Carcinogenesis, 325 Life Sciences Building, Penn State University, University Park, PA 16802, USA Date of Publication:Read More
Validating the Gene Expression of Clinically Relevant CYP450 Enzymes and Transporters in Human upcyte® Hepatocytes to Develop an In Vitro Predictive Tool for DDI
Print PDF View Full Size Research conducted by: Samaar Maalouf (1), Bruce Sherf(1), & Jack Vanden Huevel (1,2) (1) INDIGO Biosciences, Inc., 1981 Pine Hall Road, State College, PA, USA (2) Center for Molecular Toxicology and Carcinogenesis, 325 Life Sciences Building, Penn State University, University Park, PA 16802, USA Date of publication: 2017
Inhibition of Mitochondrial Gene Expression by Nucleoside Analogues and Delayed Mitochondrial Dysfunction
Print PDF View Full Size Research conducted by: Midhun Korrapati(1), Koji Toyokawa (1), Bruce Sherf (1), & Jack Vanden Huevel (1,2) (1) INDIGO Biosciences, Inc., 1981 Pine Hall Rd, State College, PA, USA (2) Center for Molecular Toxicology and Carcinogenesis, 325 Life Sciences Building, Penn State University, University Park, PA 16802, USA Date of publication: MarchRead More
Examination of Retinoid-like Compounds for Human RXRs, RARs, and RORs
Print PDF View Full Size Research conducted by: Prajakta Albrecht (1), Koji Toyokawa (1), Ewa Maddox (1), Palmer Cramer (1), Jack Vanden Huevel (1,2), & Bruce Sherf (1) (1) INDIGO Biosciences, Inc., 1981 Pine Hall Rd, State College, PA, USA (2) Center for Molecular Toxicology and Carcinogenesis, 325 Life Sciences Building, Penn State University, University Park,Read More
An Automated Cell-Based Platform for the Rapid Detection of Novel Androgen Receptor Modulators
Print PDF View Full Size Research conducted by: Brad Larson (1), Bruce Sherf (2), & Peter Banks (1) (1)BioTek Instruments, Inc., Winooski, VT, USA (2) INDIGO Biosciences, Inc., State College, PA, USA Date of Publication: March 2012
Live Cell Multiplex (LCM) Assay
Print PDF View Full Size Research conducted by: Ewa Maddox (1) & Bruce Sherf (1) (1) INDIGO Biosciences, Inc., 1981 Pine Hall Rd, State College, PA, USA Date of Publication: March 2011
Activation of farnesoid-X-receptor (FXR) by bioactive lipids
Print PDF View Full Size Research conducted by: Jerry Thompson (1), Jun Zhang (1), & Jack Vanden Huevel (1,2) (1) Center for Nutrigenomics, Penn State University, University Park, PA 16802, USA (2) INDIGO Biosciences, Inc., 1981 Pine Hall Rd, State College, PA, USA Date of Publication: March 2010