INDIGO’s assay kits and services can provide valuable information for your endocrinology research. Whether you are interested in a single-receptor assay or a full-panel study, we can help you obtain the data you need quickly.


Receptors for Endocrinology Research

Nuclear receptors are a critical part of endocrine functioning. Understanding the mechanisms underlying the involvement of nuclear receptors in the pathogenesis of endocrine disorders may offer targets for the development of new treatments, as well as creating better treatments for correcting hormone imbalances caused by endocrine disorders.


Indigo Assays for Endocrinology Research

INDIGO Biosciences offers assays for receptors that are implicated as promising therapeutic targets for endocrinology:


Endocrinology is the study of the messenger system comprising feedback loops of hormones released by internal glands. Hormones are used to communicate between organs and tissues for physiological regulation of multiple functions including autonomic functions, circadian rhythm, development and reproduction, metabolism, mood, and stress response.

There are many common endocrine disorders that cause disruptions in the endocrine system including diabetes mellitus, acromegaly, Addison’s disease, Cushing’s syndrome, and hyperthyroidism. Treatments for endocrine disorders vary depending on the specific disorder, but often focus on correcting the hormone imbalance.

Another source of study in endocrine research is from chemicals both man-made and natural that are full agonist, partial agonist, or antagonist of the receptors that function in the endocrine system. Perturbation caused by these chemicals, sometimes referred to as Endocrine Disrupting Chemicals (EDCs) can range in their physiological effects from tumorigenesis to birth defects and other developmental disorders. Many of these chemicals are lipophilic and are known to bioaccumulate in tissues. For those interested in endocrine disrupting chemicals, learn more in this white paper from INDIGO Nuclear Receptors & Endocrine / Metabolic Disruption.

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Related Information

Nuclear Receptors and Their Classifications


How Nuclear Receptor Profiling Can Determine the Fate of Your Compounds


How to Develop Testing Strategy for EDCs in Water Resources


Profiling Drug Activity of Human and Ortholog Xenobiotic-Sensing Receptors: PXR, CAR, AhR, and FXR - INDIGO Biosciences


Regulation of Steatosis in upcyte®Hepatocytes by Nuclear Receptor Agnostics


Correlation Between Cytochrome P450 Inducers and Nuclear Receptor Activation - a Screening Approach - INDIGO Biosciences


Human CYP2B6 Produces Oxylipins from Polyunsaturated Fatty Acids and Reduces Diet-Induced Obesity

Disruption of the Tumor Suppressor-Like Activity of Aryl Hydrocarbon Receptor by Arsenic in Epithelial Cells and Human Lung Cancer

Effects-Based Monitoring of Bioactive Compounds Associated with Municipal Wastewater Treatment Plant Effluent Discharge to the South Platte River, Colorado, USA

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