INDIGO’s assay kits and services can provide valuable information for your endocrinology research. Whether you are interested in a single-receptor assay or a full-panel study, we can help you obtain the data you need quickly.
Receptors for Endocrinology Research
Nuclear receptors are a critical part of endocrine functioning. Understanding the mechanisms underlying the involvement of nuclear receptors in the pathogenesis of endocrine disorders may oﬀer targets for the development of new treatments, as well as creating better treatments for correcting hormone imbalances caused by endocrine disorders.
Indigo Assays for Endocrinology Research
Endocrinology is the study of the messenger system comprising feedback loops of hormones released by internal glands. Hormones are used to communicate between organs and tissues for physiological regulation of multiple functions including autonomic functions, circadian rhythm, development and reproduction, metabolism, mood, and stress response.
There are many common endocrine disorders that cause disruptions in the endocrine system including diabetes mellitus, acromegaly, Addison’s disease, Cushing’s syndrome, and hyperthyroidism. Treatments for endocrine disorders vary depending on the specific disorder, but often focus on correcting the hormone imbalance.
Another source of study in endocrine research is from chemicals both man-made and natural that are full agonist, partial agonist, or antagonist of the receptors that function in the endocrine system. Perturbation caused by these chemicals, sometimes referred to as Endocrine Disrupting Chemicals (EDCs) can range in their physiological effects from tumorigenesis to birth defects and other developmental disorders. Many of these chemicals are lipophilic and are known to bioaccumulate in tissues. For those interested in endocrine disrupting chemicals, learn more in this white paper from INDIGO Nuclear Receptors & Endocrine / Metabolic Disruption.