INDIGO Biosciences offers cell-based luciferase reporter assay kits for the Mineralocorticoid Receptor. Our assays provide an all-inclusive luciferase reporter system that includes, in addition to MR Reporter Cells, optimized media for use during cell culture and in diluting the user’s test samples, a reference agonist, Luciferase Detection Reagent, and a cell culture-ready assay plate. INDIGO can also perform the MR assay in its own lab as a service for researchers.
INDIGO’s cell-based reporter assays allow scientists to screen and discover drugs that can be used to treat MR-related diseases. They provide an efficient way to examine a compound for its ability to regulate nuclear receptor activity in agonist, inverse-agonist, or antagonist mode using firefly luciferase reporter gene technology. Since the receptor binding controls the expression of the luciferase reporter gene, luciferase activity in the cells can be correlated directly with the activity of the receptor. Contact us today to learn more about our Mineralocorticoid Receptor assay kits and screening capabilities!