Product Description and Product Data
INDIGO’s Retinoid X Receptors Panel (RXR alpha, RXR beta, and RXR gamma) assay kit is an all-inclusive firefly luciferase reporter assay system that includes in addition to reporter cells for each RXR, optimized cell culture medium, a medium for diluting test compounds, a control agonist for each RXR, stable-glow luciferase detection reagent, detailed protocol, Protocol Quick Guide, and a cell culture-ready assay plate in strip-well format so that (if preferred) RXR alpha, RXR beta, and RXR gamma assays may be performed at different times. This panel contains sufficient materials to perform 32 RXR alpha assays, 32 RXR beta assays, and 32 RXR gamma assays in 96-well plate format.
Clear, Reproducible Results
- All-Inclusive Assay Systems
- Exceptional Cell Viability Post-Thaw
- Consistent Results Lot to Lot
|Target Type||Nuclear Hormone Receptor|
|Assay Mode||Agonist, Antagonist|
|Shelf Life||6 months|
|Shipping Requirements||Dry Ice|
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcription factors.
This PANEL of Retinoid X Receptors Reporter Assays utilizes non-human mammalian cells engineered to express distinct human RXRα (NR2B1), RXRβ (NR2B2), and RXRγ (NR2B3) proteins.
Also available as a service