Autoimmune Disease & Inflammation

INDIGO’s assay kits and services can provide valuable information for your autoimmune disease and inflammation research. Whether you are interested in a single-receptor assay or a full-panel study, we can help you obtain the data you need quickly.


Receptors for Autoimmune Disease & Inflammation Research

Nuclear receptors and other receptors are targets for autoimmune research due to their involvement in the signaling pathways for inflammation and immunity. Autoimmune diseases also cause damage to the endocrine system causing over or underproduction of certain hormones. This makes therapies that are full or partial agonists, or antagonists of nuclear hormone receptors involved in endocrine function important for managing perturbations caused by specific autoimmune diseases.


INDIGO Assays for Autoimmune Disease & Inflammation Research

INDIGO Biosciences offers assays for receptors that are implicated as promising therapeutic targets for drug discovery in autoimmune disease and inflammation:

Autoimmune Disease & Inflammation

A healthy immune system defends the body against disease and infection, but if the immune system malfunctions, it can mistakenly attack healthy cells, tissues, and organs. Collectively diseases that result from dysfunction of the immune system, whether from abnormally low activity or over activity, are called autoimmune disease. These attacks can affect any part of the body, weakening bodily function and even turn life-threatening. More than 23 million people in the United States have an autoimmune disease and there are more than 80 known types of autoimmune diseases including type 1 diabetes, rheumatoid arthritis, psoriasis, and multiple sclerosis.

Many autoimmune diseases have similar symptoms. One of the classic signs of an autoimmune disease is the redness, heat, pain, and swelling caused by inflammation. Though inflammation is critical for the body’s normal immune responses, chronic inflammation has been shown to cause tissue damage. For these reasons and others, avenues for autoimmune disease research include the role of inflammation associated with immune system response.

Treatments for autoimmune diseases vary depending on the disease, but mostly consist of ways to reduce symptoms and reduce the immune systems abnormal response. Currently, the cause for autoimmune diseases is unknown but, due to the rise of incidences of autoimmune disease, researchers suspect environmental factors play a role.

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